Computational Modeling and Simulation of the Human Duodenum

B. Hari[1], S. Bakalis[1], P. Fryer[1]
[1]The University of Birmingham, School of Chemical Engineering, Edgbaston, Birmingham, United Kingdom
Published in 2012

Worldwide attention in the computational modeling and simulation of the human intestine is increasing in order to help understand its complex behavior and improve health. Computational fluid dynamics is an essential tool to understand the mechanics and transport phenomena of the human intestine, thereby advancing the diagnosis and treatment of gastrointestinal related diseases. The aim of this work is to develop a computational fluid dynamics model of the human duodenum, which is entirely modeled with COMSOL Multiphysics 4.2a. The in-silico duodenum model consists of five different interfaces, Free and Porous Media Flow, Solid Mechanics, Moving Mesh, Particle Tracing for Fluid Flow and Transport of Diluted Species.