Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Modeling a Focused Microwave System for Transcutaneous Thermal Therapy of Breast Cancer

J. Stang, B. Fowlkes, M. Moghaddam, O. Kripfgans, and P. Carson
University of Michigan, Ann Arbor, MI, USA

A transcutaneous thermal therapy system is being developed for the targeted treatment of breast cancer cells using focused microwaves as an adjuvant to surgery, radiation, chemotherapy, and high intensity focused ultrasound (HIFU). Prior imaging studies are used to ascertain the material properties of the breast tissue, and this data is incorporated into a COMSOL Multiphysics model. Time ...

Constructing Laser-Induced In Vitro Cell Damage Model Based on Thermal Analysis using COMSOL

S. Boukhris[1], M. Denton[2], and Y. Feng[1]
[1]Computational Bioengineering and Control Lab, University of Texas at San Antonio, San Antonio, TX
[2]TASC, Inc. Biomedical Sciences and Technology Dept., Ft. Sam Houston, TX

The use of lasers in the military and everyday life is growing each year. The purpose of the current research is to take full advantage of this new spatially-resolved thermal data to construct a mathematical and numerical model for laser-induced damage using COMSOL Multiphysics. The microthermography data were extracted for vertical and horizontal lines through the laser-exposed area of cell ...

Effect of Calcification Properties on Stress in Models of Atherosclerotic Plaque

C. Buffinton, P. Rogerson, and D. Ebenstein
Bucknell University
Lewisburg, PA

The effects of calcifications on arterial wall stress have been largely ignored, in part because the material properties of the calcified areas were taken to be the same as the fibrous plaque, and in part because they are often assumed to have a stabilizing influence. Recent measurements suggest that their stiffness should be more similar to bone. A computational model is indicated for this ...

Solving Calcium Spatiotemporal Diffusion Using COMSOL Multiphysics® Software - new

L. Garber[1,2], G. S. B. Williams[2], W. J. Lederer[2]
[1]Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
[2]Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA

This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of sarcoplasmic reticulum, lack of contractile apparatus). We explored the role of the t-tubular network on ...

Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties - new

K. Cluff[1], H. Mehraein[1], G. Jayakumar[2]
[1]Bioengineering, Wichita State University, Wichita, KS, USA
[2]Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical imaging and computational fluid dynamics (CFD) in a time dependent study allowed the determination of wall ...

Analysis of Heat Transfer in a Complex Three Dimensional Structure Fabricated by Additive Manufacturing - new

C. Settle[1], K. Hoshino[1]
[1]Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA

The goal of this study was to create a three dimensionally designed biomedical device with multiple functionalities and analyze its simulated heat transfer. The device would be fabricated through additive manufacturing; specifically electron beam melting (EBM). EBM has a feature size constraint of 1 mm (acceptable for this design) and is only capable of manufacturing titanium alloys [2]; a ...

FEM Simulation of Magnetically Triggered Hydrogel Micro Particles as Advanced Drug Carriers - new

O. Yassine[1], M. Kavaldzhiev[1], J. Kosel[1], Q. Li[1], A. Alfadhel[1], A. Zaher[1]
[1]Electrical Engineering Division, CEMSE Group, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia

Thermally responsive microgel Poly (N-isopropylacrylamide), particles are embedded with iron oxide nanobeads creating magneto-thermally responsive microparticles (MTMs). The magnetic losses in the nanobeads activate the PNIPAM by heating it up to its lower critical solution temperature (LCST), which is approximately 32°C. The COMSOL Multiphysics® software with Heat Transfer Module is used to ...

Multiscale Electromagnetic Modeling of Contractions in the Pregnant Uterus - new

V. Tidwell[1], P. LaRosa[2], M. Zhang[1], H. Eswaran[3], A. Nehorai[1]
[1]Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO, USA
[2]Monsanto Company, Technology Pipeline Solutions, St. Louis, MO, USA
[3]OB/GYN Department, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Uterine contractions during pregnancy are currently poorly understood – experts disagree on the mechanisms by which contractions propagate through the organ and the structural layout of the uterine muscle fibers. We have developed a multi-scale model of the uterus, at the cellular, tissue, and organ levels. By comparing simulated abdomen-level magnetic field readings from our model to clinical ...

Magnetostatic-Magnon Sensors for Microwave Microscopy of Biological Structures - new

E. Hollander[1], E. O. Kamenetskii[1], R. Shavit[1]
[1]Microwave Magnetic Laboratory, Department of Electrical and Computer Engineering, Ben Gurion University of the Negev, Beer Sheva, Israel

Microwave sensing and monitoring is very attractive for biological applications because of their sensitivity to water and dielectric contrast. Direct detection of biological structures in microwave frequencies and understanding of the molecular mechanisms of microwave effects is considered as a problem of a great importance. Nowadays, however, microwave technique for localized testing biological ...

Design of Multiple Ground System for Maternal Defibrillation - new

A. Jeremic[1], E. Khoshrowshahli[2]
[1]Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada
[2]Biomedical Engineering, McMaster University, Hamilton, ON, Canada

Although cardiac arrest may be statistically insignificant event financial and more important emotional costs in such cases are quite devastating. In this paper we study the effects of multiple grounding pads. Namely, we believe that by placing multiple pads in the lower abdominal part we would be able to decrease the current density that would be dissipated to fetus and amniotic liquid. ...

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