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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Munich 2023

Electrophoretic Focusing and Navigation for Intranasal Target Drug Delivery

X. Si[1]
[1]Calvin College, Grand Rapids, MI, USA

Direct nose-to-brain drug delivery circumvents the blood-brain-barrier and has multiple advantages over intravenous delivery. However, its application is limited by the extremely low delivery efficiency to the olfactory region. This study evaluated the feasibility of targeted drug ... Read More

Singlet Oxygen Modeling for PDT Incorporating Local Vascular Oxygen Diffusion

T. C. Zhu[1], B. Liu[1]
[1]University of Pennsylvania, Philadelphia, PA, USA

Singlet oxygen (1O2) is the major cytotoxic agent that kills cells during photodynamic therapy (PDT). Based on a previously-developed model, the distance-dependent reacted 1O2 can be numerically calculated using finite-element method. We improved the model to include microscopic kinetic ... Read More

Modeling the Effect of Porosity on the Elastic Properties of Synthetic Graphite Using CT Scans and the Finite Element Method

G. Sowa[1], R. Paul[1], R. Smith[1]
[1]GrafTech International Inc., Parma, OH, USA

Predicting the physical properties and performance of carbon and graphite materials based on the microstructure of the finished material is a challenging endeavor. This paper discusses the process and workflow for measuring and analyzing the pore structure of graphite by combining ... Read More

Modeling Inertial Focusing in Straight and Curved Microfluidic Channels

J. Martel[1], N. Elabbasi[2], D. Quinn[2], J. Bergstrom[2], M. Toner[1]
[1]BioMEMS Resource Center, Massachusetts General Hospital, Boston, MA, USA
[2]Veryst Engineering, Needham, MA, USA

Inertial focusing is a promising microfluidic technique for separating and concentrating cells of interest, processes routinely utilized in many medical procedures. This phenomenon is characterized by suspended particles in a flow spontaneously migrating across streamlines to equilibrium ... Read More

Computational Modeling of the Electrohydrodynamics Influencing Trace Mercury Adsorption within Electric Utility Electrostatic Precipitators

H. Clack[1]
[1]University of Michigan, Ann Arbor, MI, USA

Anthropogenic mercury (Hg) emissions increase the risk of neurological and neonatal health effects in humans through fish consumption. There are several technological approaches to controlling mercury emissions from coal combustion, including the injection of a powdered mercury sorbent ... Read More

Computational Fluid Dynamics for Microreactors Used in Catalytic Oxidation of Propane

S. Odiba[1], M. Olea[1], S. Hodgson[1], A. Adgar[1]
[1]Teesside University, School of Science and Engineering, Middlesbrough, United Kingdom

This research deals with the design of suitable microreactors for the catalytic oxidation of volatile organic compound (VOCs), using propane as a model molecule. The microreactor considered consists of eleven parallel channels, in which an Au/Cr/γ-Al2O3-catalyzed combustion reaction ... Read More

SD Numerical Simulation Technique for Hydrodynamic Flow Gas-Solids Mixing

I. Mantilla[1], S. De Vicente[2]
[1]National University of Engineering, Lima, Perú
[2]Polytechnic University of Madrid, Madrid, Spain

We formulate a new mathematical model of gas-solids mixing hydrodynamic flow [1] in a combustion chamber with a fluid bed system used in the combustion of mineral coal waste. This model in study is called Model Gas-Solids Mixing and it is constructed by averaging the conservation ... Read More

Application of COMSOL Multiphysics® Pipe Flow Module to Develop a High Flux Isotope Reactor (HFIR) System Loop Model

P. K. Jain[1], D. Wang[1], J. D. Freels[1]
[1]Oak Ridge National Laboratory, Oak Ridge, TN, USA

Oak Ridge National Laboratory’s High Flux Isotope Reactor (HFIR) is the highest flux reactor-based source of neutrons for research in the United States. Thermal and cold neutrons produced by HFIR are used to study physics, chemistry, material science, engineering, and biology. Currently, ... Read More

Advancements in Carbon Dioxide and Water Vapor Separations Using COMSOL Multiphysics®

J. Knox[1], R. Coker[1], R. Cummings[1], C. Gomez[1], G. Schunk[1]
[1]NASA, Marshall Space Flight Center, Huntsville, AL, USA

Some NASA efforts are focused on improving current systems that utilize fixed beds of sorbent pellets by evaluating structured sorbents, seeking more robust pelletized sorbents, and examining alternate bed configurations to improve system efficiency and reliability. For the bulk ... Read More

Inductive Conductivity Measurement of Seawater

R. W. Pryor[1]
[1]Pryor Knowledge Systems, Inc., Bloomfield Hills, MI, USA

The conductivity of seawater directly correlates with the concentration of dissolved salts. This model demonstrates a new approach to the methodology of inductive conductivity measurement of seawater and other liquids. COMSOL Multiphysics® was used to build a parametrically swept model ... Read More

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