E. Lacatus , G. C. Alecu , A. Tudor ,
 Politehnica University of Bucharest, București, Romania
At the forefront of a new generation of sensors graphene and graphene composite materials are intensively studied for medical and biosensing applications. The outstanding electrical, mechanical and quantum properties of graphene make them a promising material solution to overlap the existing gap between biological and non-biological systems into a continuum like-viscoelastic integrated model. ...
C. Gavrila, A. Ghiaus, and I. Gruia
Technical University of Civil Engineering Bucharest, Faculty of Building Services, Bucharest, Romania
University of Bucharest, Faculty of Physics, Bucharest, Romania
A dynamic mathematical model, based on physical and transport properties and mass and energy balances, was developed for the simulation of unsteady convective drying of agricultural products (fruits and vegetables) in static bed conditions. The model utilizes water sorption isotherm equations and the change in solid density due to the shrinkage phenomenon. The aim of this article is to describe ...
M. K. Gobbert, X. Huang, S. Khuvis, S. Askarian, B. E. Peercy
University of Maryland - Baltimore County, Baltimore, MD, USA
This paper presents information on techniques needed in COMSOL Multiphysics® to enable computational studies of coupled systems of PDEs for time-dependent non-linear problems. Furthermore, we demonstrate how to use data files as input for initial conditions. To illustrate the techniques, we consider a system of two time-dependent non-linear PDEs from mathematical biology that couples an ...
A Practical Method to Model Complex Three-Dimensional Geometries with Non-Uniform Material Properties Using Image-based Design and COMSOL Multiphysics®
J. Cepeda, S. Birla, J. Subbiah, H. Thippareddi
Department of Food Science & Technology, University of Nebraska, Lincoln, NE, USA
Department of Biological Systems Engineering, University of Nebraska, Lincoln, NE, USA
Geometries with heterogeneous material properties are typically defined as a set of multiple parts, each part representing a different material. However, assembling or defining the individual parts of complex geometries can be difficult. A practical method based on image-based mesh generation, a custom algorithm for labeling materials, and interpolation functions of COMSOL Multiphysics® can be ...
G. Mach , C. Sherif , U. Windberger , A. Gruber ,
 Vienna University of Technology, Cerebrovascular Research Group Vienna, Vienna, Austria
 Hospital Rudolfstiftung, Cerebrovascular Research Group Vienna, Vienna, Austria
 Medical University Vienna, Cerebrovascular Research Group Vienna, Vienna, Austria
Usually, when calculating the blood flow in cerebral arteries and intracranial aneurysms, blood is modeled as a Newtonian fluid, neglecting its shear-thinning behavior. Since flow diverting devices slow down the blood flow in the aneurysm sack, the accuracy of this assumption had to be reviewed. A Carreau Yasuda model is introduced as a non-Newtonian model for blood viscosity. CFD simulations of ...
University of Miami, Miami, FL, USA
Insulin released by the beta-cells of pancreatic islets is the main regulator of glucose homeostasis, hence, insulin secretion models are of considerable interest for many possible applications. Building on our previous oxygen consumption and cell viability model for avascular islets of Langerhans, we developed an exploratory insulin secretion model that couples the hormone production rate to ...
M. Kaushik , S. Katti , V. Saradesai , P. Naragund , P. Vidhyashree , A. K. V. Nandi 
 B.V. Bhoomaraddi College of Engineering and Technology, Hubli, India
This article describes the design of MEMS based cantilever structure intended for determination of blood group and it is compared with manual method. Cantilever structure design has a sensing layer and when a blood sample comes in contact with this, results in coagulation. The surface tension in turn occurs due to chemical and biological reactions of antigen and antibodies resulting in ...
K. Cluff, L. Saeednia, H. Mehraein , R. Asmatulu
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been used as in-situ hydrogel formulations. These polymeric formulations can form gels at body temperature while ...
Numerical Study on Mechanical Properties of Stents with Different Materials during Stent Deployment with Balloon Expansion.
P. Ghosh, K. DasGupta, D. Nag, and A. Chanda
School of Bio Science & Engineering, Jadavpur University, Kolkata, West Bengal, India
Mechanical Engineering Department, Jadavpur University, Kolkata, West Bengal, India
The main reason for stent implantation is to provide mechanical support to the arterial wall. So it is important to consider the different mechanical properties of different stent materials while studying the stent implant’s efficacy. The present study gives a comparative overview of mechanical aspects of different stent materials which are most commonly used in angioplasty. Deformation ...
D. Iber, D. Menshykau, P. Germann, L. Lermuzeaux[2,3]
D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
D-BSSE, ETH Zurich, Basel, Switzerland
Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France
Morphogenesis is a tightly regulated process that has been studied for decades. Previously we developed data-based mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to better understand the underlying regulatory logic. In our previous papers on simulating organogenesis in COMSOL Multiphysics® we discussed methods to efficiently solve ...