J. F. Hansen ,
 Thoratec Corporation, CA, USA
When an electronic device is worn for extended periods, possibly in direct contact with human skin, heat must be safely transferred away from the device, without exceeding standards and regulatory temperature limits on the skin and on the exposed surfaces of the device. Heat transfer is dominated by convective heat transfer to the surrounding air (possibly trapped air under clothing), and by ...
D. Iber, D. Menshykau
D-BSSE, ETH Zurich, Basel, Switzerland
Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to better understand the underlying regulatory logic. Organ size changes dramatically during development, and tissues are composed of several layers that may expand ...
G. Zhang , Y. Zhao , J. Brcka , J. Faguet ,
 Clemson University, Clemson, SC, USA
 Tokyo Electron U.S. Holdings, Inc., Austin, TX, USA
We have simulated alignment and movement of multiple particles under Dielectrophoresis (DEP) using the Particle Tracing Module in COMSOL Multiphysics® software with particle-particle interaction taken into consideration. We are able to do efficient modeling for both 2D and 3D cases. With this work, we are able to shed important insights into the process of pearl chain formation, antenna-like ...
H. Ghosh , C. Roychaudhuri ,
 Indian Institute of Engineering Science and Technology (IIEST), Shibpur, Howrah, West Bengal, India
This paper explores surface charge modulated ionic conductance of closed solid-state nanopores for explaining significant nonlinear length dependent variation in ionic current in such nanopore biosensors with a view to design improved sensors without increasing fabrication cost for biomolecule detection. Although extensive work has been done in modeling open pore conductance, closed nanopores ...
刘孟杰 , 付芳芳 , 李萌 
动脉瘤破裂是引起蛛网膜下腔出血的一种主要原因。结合 COMSOL Multiphysics® 灵活的几何建模特性以及强大的流体仿真求解能力，本文分别对两组不同大小关系的 MCA 动脉瘤理论模型进行了仿真建模分析。通过模拟分析，获得了动脉瘤球囊体长度和宽度与动脉瘤基底宽度不同比例条件下的动脉瘤速度、压力、壁面切应力（WSS）等参数的变化规律，分析了几何形态与动力学参数之间的关系。模拟结果显示：1、宽颈动脉瘤，瘤体内部旋流强度较之窄颈动脉瘤更强，中心区流速更低，更有利于形成血栓而且顶点处压力更大，更易破裂。2、增大动脉瘤宽度与基底直径的比值，顶点处 WSS 呈非线性增长，但最大值低于 WSS 安全范围的下限值，破裂危险性依然很高；3、动脉瘤宽度与基底直径不同比例下的最大的 WSS 均是主要集中在动脉瘤与载瘤血管结合处（第一剪应力集中区），对血管壁生物组织力学特性影响严重；WSS ...
M. Christian, S. Firebaugh, A. Smith
United States Naval Academy, Annapolis, MD, USA
This project utilizes the heat transfer module of the COMSOL Multiphysics environment to model the effects that an ohmic heating probe will have on neural tissue. The model quantifies the thermal impact of active components embedded on a neural micro probe by solving the Penne’s bioheat equation with an external MATLAB function to determine the heat generation along the length of the probe. The ...
J. Persad , S. Rocke ,
 Department of Electrical and Computer Engineering, University of the West Indies, St. Augustine, Trinidad and Tobago
This work aims to investigate the behaviour of a simple interdigital sensor structure for glucose monitoring in response to distortions in the skin-topology and differences in skin undulation during use. The study then extends to consider a flexible sensor structure which is better able to contour to the skin variations. The simulation work shows that skin distortions and undulation ...
D. Iber, D. Menshykau, P. Germann, L. Lermuzeaux[2,3]
D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
D-BSSE, ETH Zurich, Basel, Switzerland
Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France
Morphogenesis is a tightly regulated process that has been studied for decades. Previously we developed data-based mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to better understand the underlying regulatory logic. In our previous papers on simulating organogenesis in COMSOL Multiphysics® we discussed methods to efficiently solve ...
P. Priya , B. D. Pant ,
 Birla Institute of Technology and Science Pilani, Pilani, Rajasthan, India
 CSIR-Central Electronics Engineering Research Institute, Pilani, Rajasthan, India
In this paper, a free membrane is used as a receiver to increase the capacitance and therefore the resolution of the flow meter. For the current application, from the wavelength of sound wave in soft tissue (c= 1540 m/s) the resolution was calculated to be 0.48 mm. This gives the first Eigen frequency of the capacitive structure according to which the poly silicon membrane was designed. After ...
Design of a Dielectrophoretic Based Micropipette for Gene Expression Applications Using COMSOL Multiphysics® Software
D. Wijesinghe , K. Nawarathna ,
 Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND, USA
We have used COMSOL Multiphysics® software to design a micropipette for single -cell gene expression profiling. The micropipette design allows us to insert it into a single-cell to extract genes through dielectrophoresis. As dielectriphoretic force depends on the applied electric field (E) and its gradient (∇E^2), we have successfully used COMSOL to calculate E and ∇E^2 in the vicinity of the ...