Numerical Simulation of the Functional Electromagnetic Stimulation of the Human Femoral Bone using COMSOL
Y. Haba, W. Kröger, H. Ewald, R. Souffrant, W. Mittelmeier, and R. Bader
Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, University of Rostock, Rostock, Germany
Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
In the present study we determined the relative conductivities and permittivities of fresh cortical and cancellous bone measuring human femoral heads in different slices of 1 mm thickness. The identified conductivities of human trabecular bone are used for the electromagnetic field simulation by means of COMSOL using a Micro-Computed Tomography (Micro-CT) model. The calculated model depends on a ...
A. Candeo and F. Dughiero
Department Electrical Engineering, University of Padova, Padova, Italy
Radiofrequency Ablation (RFA) represents a valid alternative for treating liver metastases in medically complicated patients. Conventional devices currently operate at 500 kHz, due to good conducting properties of tissues. However, the use of lower frequencies (i.e. 20 kHz) has been recently reported to enhance the treatment effectiveness, due to a more pronounced difference in electrical ...
A. Chanda, A.R. Choudhury, G. Ray, K. Dasgupta, and D. Nag
Jadavpur University, Kolkata, West Bengal, India
Atherosclerosis in arteries is caused by the formation of stenosis : fatty depositions, on the artery wall. In current medicine, the practice is to observe the maximum percentage occlusion at any arbitrary cross-section and diagnose the patient on that basis, which might not always present the real picture due to non-uniformity of the stenosis thickness. The present work attempts to simulate the ...
Three-Dimensional Finite Element Modeling of Current Density in Maternal Transthoracic Defibrillation
A. Jeremic, J. Potts, E. Khosrowshahli
McMaster University, Hamilton, ON, Canada
McMaster University Hospital, Hamilton, ON, Canada
Although the cardiac arrest in pregnancy is a rare event it can have significant impact in terms of age of mother, mortality of unborn children and consequently long-term effect. One of the commonly used procedures in resuscitation is defibrillation. With recent advances in understanding pathophysiologies in pregnant women it became more obvious that previous studies should be extended to ...
M. Carfagna , A. Grillo ,
 Dipartimento di Scienze Matematiche, Politecnico di Torino, Italy
The numerical results of the unconfined compression test on a sample of Articular Cartilage (AC) are discussed. AC is modelled as a load-bearing, deformable, fiber-reinforced material filled with an interstitial fluid and comprising statistically oriented collagen fibers, chondrocytes, and a matrix of proteoglycans. A strain energy is assigned to characterize the mechanical behavior of the ...
Advancing Regulatory Science through Integrative Engineering with COMSOL Multiphysics® Software Modeling
G. Zhang 
 Department of Bioengineering, Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
The US Food and Drug Administration (FDA) faces significant challenges in its regulatory approval processes due to a lack of relevant science, and many practices are limited by laws enacted in the previous century . Therefore, in recent years, the FDA has identified the need for advancements in regulatory science and innovation. In a broader sense, advancing regulatory science is not just ...
V. Rakesh, and A. Datta
Dept. of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA
Although microwave heating has been studied in great detail, microwave combination heating has not. This work investigated this in a novel microwave combination system that heats the sample through a combination of microwaves and hot air. The study used a coupled electromagnetics-multiphase porous media model in COMSOL to determine the effect of combining different heating modes on heating ...
An Elastic and Hyperelastic Material Model of Joint Cartilage - Calculation of the Pressure Dependent Material Stress in Joint Cartilage
T. Reuter, and M. Hoffmann
Research Centre of Medical Technology and Biotechnology
Bad Langensalza, Germany
In this paper we introduce a elastic and hyperelastic model to describe the pressure dependent material stress in joint cartilage. We used the pressure dependent E-modulus E = f(s) to calculate the material stress. E = f(s) is a degree 4 polynomial . The indentor was pressed 0.4 mm into the tissue. The results show that the maximal stress at the contact zone between indentor and cartilage ...
A Study on Nutrient Mass Transport through Porous Channeled Flat Sheet Membrane and Prediction of Maximum Scaffold Thickness for Viable Cell Culture (In-vitro) by 3D Modeling for Tissue Engineering Application
N. M. S. Bettahalli, B. J. Papenburg , D. S. Stamatialis , M. Wessling 
University of Twente, Enschede, The Netherlands & BMS College of Engineering, Bangalore, India
University of Twente, Enschede, The Netherlands
RWTH Aachen University
Tissue engineering (TE) is a multidisciplinary field involving principles of engineering and life sciences to improve the health and quality of life by repairing, restoring, maintaining, or enhancing tissue and organ function using cells, scaffolds, and growth factors alone or in combination. There are several artificial tissues that are already being used which include fabricated skin, ...
C. Nadovich[1, 2], W. D. Jemison, J. A. Stoute, C. Spadafora
Lafayette College, Easton, PA, USA
Clarkson University, Potsdam, NY, USA
Pennsylvania State University, Hershey, PA, USA
INDICASAT AIP, Ciudad del Saber, Panama
A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities and exposure configuration. To address diverse requirements, three different applicators were developed: a ...