Extending Engineering Simulations to Scientists: Food Safety and Quality Prediction Using COMSOL Multiphysics® and LiveLink™ for Excel®
A. Warning, A. K. Datta
Cornell University, Ithaca, NY, USA
The objective of this study was to develop an easy to use interface in Excel® that connects to not only the solvers in COMSOL Multiphysics®, but also existing databases of food properties, foodborne pathogenic microorganisms kinetics, and chemical kinetics, creating a comprehensive simulation software to predict food safety and quality. The user interface allows the user to select the food, ...
P. Silva, J.A. Ferreira, P. de Oliveira
Coimbra Institute of Engineering, CMUC, Coimbra, Portugal
Department of Mathematics University of Coimbra, CMUC, Coimbra, Portugal
The aim of the poster is to present a coupled 2D mathematical model to predict the evolution of drug concentration - in the cornea and in the anterior chamber of the eye - when therapeutic lenses are used (Figure 1). The mathematical model takes into account (i) diffusion processes in several compartments of the eye (therapeutic lens, cornea and anterior chamber); (ii) metabolic consuming ...
M. Nebyla, M. Pribyl
Institute of Chemical Technology, Prague, Department of Chemical Engineering, Prague, Czech Republic
We introduce a mathematical model of signal transmission in simple epithelial layers. The mathematical model consists of reaction-transport equations for extracellular ligands, cellular receptors, ligand-receptor complexes and a ligand releasing protease. We consider diffusion and nonstationary convective transport of protein ligands in the extracellular space. The study was carried out using ...
J.M. Gozálvez-Zafrilla, A. Santafé-Moros, J.L. Díez-Ruano, J. Bondia
Institute for Industrial, Radiophysical and Environmental Safety (ISIRYM) - Universitat Politècnica de Valencia, Valencia, Spain
Instituto Universitario de Automática e Informática Industrial (AI2) - Universitat Politècnica de Valencia, Valencia, Spain
Microdialysis is a technique of continuous glucose monitoring in diabetic patients. In microdialysis, a saline serum is perfused into a microdialysis probe. Glucose pass from the plasmatic fluid through the porous membrane. The glucose concentration in the dialysate obtained is measured by an external analytical device. This preliminary work aimed to obtain a model to relate glucose ...
C. Nadovich[1, 2], W. D. Jemison, J. A. Stoute, C. Spadafora
Lafayette College, Easton, PA, USA
Clarkson University, Potsdam, NY, USA
Pennsylvania State University, Hershey, PA, USA
INDICASAT AIP, Ciudad del Saber, Panama
A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities and exposure configuration. To address diverse requirements, three different applicators were developed: a ...
G. Bonmassar, and A. Golby
AA. Martinos Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
Department of Neurosurgery, Brigham and Women’s Hospital, Boston, Massachusetts, USA
A new type of MRI compatible intracranial electrode based on Polymer Thick Film (PTF) is presented and studied using COMSOL Multiphysics. The geometry considered was a two-dimensional cross section cut of 5 mm thick electrodes with 5 cm leads on top of a 2×10 cm slab representing Gelfilm, or the substrate. The resistive leads were compared with metallic leads to estimate the ...
M. Blaziková, J. Malínský, D. Stanek, and P. Herman
Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
Institute of Experimental Medicine, Prague, Czech Republic
Institute of Molecular Genetics, Prague, Czech Republic
Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the Cajal body. We have previously shown that the free diffusion model does not fully describe the snRNP motion ...
N. Mane, A. Gaikwad
Department of Instrumentation, Cummins College of Engineering, Pune, Maharashtra, India
Micro electro-mechanical system (MEMS) is rapidly growing area of interest for a broad spectrum of applications. One particularly fast-growing area is biomedical applications for micromaching technologies. One application of interest to the biomedical industry is the development of microneedles. MEMS technology brings new means for biomedicine field. Patch-based transdermal drug delivery offers ...
K. Funamoto, I.K. Zervantonakis, R.D. Kamm
Tohoku University, Sendai City, Miyagi, Japan
Massachusetts Institute of Technology
Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.
Electrical Response and Thermal Damage Assessment of Cutaneous and Subcutaneous Tissues to Noninvasive Radiofrequency Heating: A Computational Modeling Study
A. González-Suárez[1,2], J. N. Jimenez-Lozano, W. Franco
Wellman Center for Photomedicine, Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA
Biomedical Synergy, Electronic Engineering Department, Universitat Politècnica de València, Valencia, Spain
ZELTIQ Aesthetics, Inc., Pleasanton, CA, USA
Electromagnetic radiofrequency (RF) sources are widely used to heat up cutaneous and subcutaneous tissues. The subcutaneous morphology of tissue consists of a fine, collagenous and fibrous septa network enveloping clusters of adipocyte cells; however, it is commonly regarded as a homogeneous fat layer in computational models. In the present study the objective is to assess the effect of the ...