Modeling of Silicon Piezoresistive Pressure Sensor: Application to Prevent Some Diabetes Complications
F. Kerrour, A. Beddiaf, M. Benabbas-Marir
MODerNa Laboratory, University Mentouri, Constantine, Algeria
Several analytical solutions describing the mechanical behavior of a silicon micro membrane deflection, perfectly embedded and subjected to a uniform and constant pressure have been proposed. The obtained results are compared with those obtained by using COMSOL software for a rectangular diaphragm deflection. COMSOL Multiphysics is powerful software for solving problems based on partial ...
S. Mackintosh, J. Rodgers, S.P. Blythe
Lifescan Scotland, Inverness, Scotland
This paper describes the modeling of a blood glucose sensor using COMSOL Multiphysics. Chemical species interaction and diffusion, coupled with electrochemical oxidation of multiple blood species produced a powerful working model used in developing and refining a range of blood glucose sensors for the commercial market.
A. Lucantonio, P. Nardinocchi, L. Teresi
Università degli Studi La Sapienza, Roma, Italy
LaMS - Modelling & Simulation Lab, Università degli Studi Roma Tre, Roma, Italy
Polymer gels belong to the realm of soft active materials as they are capable of responding to a non-mechanical stimulus – the permeation of a solvent – with a mechanical action – a volume change, thanks to the coupling between different physics. This mechanism of coupling can be exploited in a wide range of applications, including biomedical devices, making crucial the understanding of the ...
P. Silva, J.A. Ferreira, P. de Oliveira
Coimbra Institute of Engineering, CMUC, Coimbra, Portugal
Department of Mathematics University of Coimbra, CMUC, Coimbra, Portugal
The aim of the poster is to present a coupled 2D mathematical model to predict the evolution of drug concentration - in the cornea and in the anterior chamber of the eye - when therapeutic lenses are used (Figure 1). The mathematical model takes into account (i) diffusion processes in several compartments of the eye (therapeutic lens, cornea and anterior chamber); (ii) metabolic consuming ...
M. Alshareef, A. Alshareef, V. Krishna, M. Kindy, T. Shazly
College of Medicine, Medical University of South Carolina, Charleston, SC, USA
Department of Biomedical Engineering, Duke University, Durham, NC, USA
Department of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA
Department of Mechanical Engineering, University of South Carolina, Columbia, SC, USA
The incidence of spinal cord injury (SCI) in the US is approximately 12,000 individuals annually, due to various forms of trauma and disease. Diminished flow over a prolonged period of time can cause permanent spinal damage. We constructed a 3D finite element model of the spinal cord to examine the role of compressive loading on spinal blood flow. It was found that the type of forces on the ...
H. Chen-Mayer, R.E. Tosh
National Institute of Standards and Technology, Gaithersburg, MD, USA
The radiation dose produced by an x-ray CT scanner to the patient is conventionally referenced to measurements performed by an ionization chamber in a phantom. On a fundamental level, the radiation absorbed dose, J/kg, can be determined directly by the temperature rise in the absorbing material. We model the temperature response in a high density polyethylene (HDPE) phantom. Use of ...
T.C. Zhu, B. Liu, X. Liang
University of Pennsylvania, Philadelphia, PA, USA
Singlet oxygen (1O2) is the major cytotoxic agent during photodynamic therapy (PDT). A previously developed model that incorporates the diffusion equation for the light transport in tissue and the macroscopic kinetic equations for the generation of the singlet oxygen, can be used to numerically calculate the distance-dependent reacted 1O2 using finite-element method (FEM). The formula of reacted ...
A Study on Nutrient Mass Transport through Porous Channeled Flat Sheet Membrane and Prediction of Maximum Scaffold Thickness for Viable Cell Culture (In-vitro) by 3D Modeling for Tissue Engineering Application
N. M. S. Bettahalli, B. J. Papenburg , D. S. Stamatialis , M. Wessling 
University of Twente, Enschede, The Netherlands & BMS College of Engineering, Bangalore, India
University of Twente, Enschede, The Netherlands
RWTH Aachen University
Tissue engineering (TE) is a multidisciplinary field involving principles of engineering and life sciences to improve the health and quality of life by repairing, restoring, maintaining, or enhancing tissue and organ function using cells, scaffolds, and growth factors alone or in combination. There are several artificial tissues that are already being used which include fabricated skin, ...
N. Mane, A. Gaikwad
Department of Instrumentation, Cummins College of Engineering, Pune, Maharashtra, India
Micro electro-mechanical system (MEMS) is rapidly growing area of interest for a broad spectrum of applications. One particularly fast-growing area is biomedical applications for micromaching technologies. One application of interest to the biomedical industry is the development of microneedles. MEMS technology brings new means for biomedicine field. Patch-based transdermal drug delivery offers ...
K. Funamoto, I.K. Zervantonakis, R.D. Kamm
Tohoku University, Sendai City, Miyagi, Japan
Massachusetts Institute of Technology
Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.