Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Deformable Image Registration for Pleural Photodynamic Therapy

B. Liu[1], T. C. Zhu[1]
[1]Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

Deformable image registration is a form of medical image processing that can provide insights into the development of phenomenon and variation in normal anatomical structure over time. Prior to post-operative pleural photodynamic therapy (PDT), a series of CT scans of lungs will be acquired. During PDT treatment, an infrared navigation system is used to contour the lungs and provide real-time ...

Solving Calcium Spatiotemporal Diffusion Using COMSOL Multiphysics® Software - new

L. Garber[1,2], G. S. B. Williams[2], W. J. Lederer[2]
[1]Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
[2]Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA

This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of sarcoplasmic reticulum, lack of contractile apparatus). We explored the role of the t-tubular network on ...

Blood Flow Patterns in a Patient Specific Right Coronary Artery with Multiple Stenoses - new

B. Liu[1]
[1]Department of Mathematics, Monmouth University, West Long Branch, NJ, USA

Atherosclerotic lesions preferentially develop in certain regions like bifurcations, branches, and bends [1, 2]. A possible explanation for such a preferential localization of atherosclerosis is that the geometry of the vessel influences the blood flow pattern. It suggests that the arterial geometry plays an important role in determining the localized blood flow information. Thus hemodynamic ...

Multiphysics Modeling of a Grain Storage Chamber - new

P. Guha[1], P. Sharma[1], V. Malhotra[1], S. Mishra[1]
[1]CSIR - Central Scientific Instruments Organisation, Chandigarh, India

Proper storage of grains depends on minimizing attacks of insects, fungi, mites, etc. Development of such pests can be controlled by controlling the temperature of the storage chamber. Hence, before designing grain storage chambers, mathematical modeling and numerical simulations should be performed to predict the temperature distributions. Changes in storage temperature may occur due to several ...

Numerical Homogenization in Multi-scale Models of Musculoskeletal Mineralized Tissues

A. Gerisch[1], S. Tiburtius[1], Q. Grimal[2], and K. Raum[3]
[1]Technische Universität Darmstadt, Darmstadt, Germany
[2]Laboratoire d’Imagerie Paramétrique, UPMC, Paris, France
[3]Julius Wolff Institut & Berlin-Brandenburg School for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany

Musculoskeletal mineralized tissues (MMTs), e.g. bone, are hierarchical composite materials. Their effective elastic properties at different scales are of interest for computational studies of the MMT’s response to mechanical loading but also to realistically simulate implant osseointegration. We combine multi-scale and multi-modal experimental techniques with mathematical modelling of MMTs ...

A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry

Kristian Dreij[1], Qasim Ali Chaudhry[2], Bengt Jernström[1], Ralf Morgenstern[1], and Michael Hanke[2]
[1]Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
[2]School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden

A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. ...

A Simplified Numerical Model for Simulating Sliding Door and Surgical Staff Movement in an Operating Theater

C. Balocco[1]
[1]Dipartimento di Energetica, Università di Firenze, Firenze, Italy

This paper deals with a numerical investigation on sliding door and people moving effects on the indoor climate of a standard ISO5 class OT with an ultraclean air filter system and a total ceiling unidirectional diffuser. A simple method to analyze the effects on the OT climate by different sliding door conditions combined with crossing persons and persons with a stretcher crossing is provided. ...

3-Dimensional Blood Cooling Model inside a Carotid Bifurcation

R. Sikorski[1], T. Merrill[1]
[1]Rowan University, Glassboro, NJ, USA

Stroke is caused by an interruption of brain blood supply and is one of the leading causes of death and disability. A mild reduction of 2-5°C in tissue temperature through hypothermia has shown reduced tissue infarct size, increased tissue recovery, and positive neurological effects. This paper seeks to predict the outlet blood temperature in the common carotid bifurcation branches. In our ...

FEM Simulation of Magnetically Triggered Hydrogel Micro Particles as Advanced Drug Carriers - new

O. Yassine[1], M. Kavaldzhiev[1], J. Kosel[1], Q. Li[1], A. Alfadhel[1], A. Zaher[1]
[1]Electrical Engineering Division, CEMSE Group, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia

Thermally responsive microgel Poly (N-isopropylacrylamide), particles are embedded with iron oxide nanobeads creating magneto-thermally responsive microparticles (MTMs). The magnetic losses in the nanobeads activate the PNIPAM by heating it up to its lower critical solution temperature (LCST), which is approximately 32°C. The COMSOL Multiphysics® software with Heat Transfer Module is used to ...

Detection of E.coli Cell using Capacitance Modulation

A.K. Dwivedi, R.M. Patrikar, R.B. Deshmukh, and G. Pendharkar
Visvesvaraya National Institute of Technology, Nagpur, Maharashtra, India

Testing and verification is very important to increase reliability of a system. In water analysis its purity is verified using different test methods. Biosensors are very useful to detect the microorganisms present in water. This paper presents a method to detect E.coli bacteria in water depending upon the capacitance modulation in the presence and absence of E.coli cell, which is simulated in ...

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