M. R. Naik
Nitte Meenakshi Institute of Technology, Bengaluru, Karnataka, India
In a modern IC design, the capability of predicting the temperature profile is critically important as well as cooling and related thermal problems are the principal challenges. To address these challenges, thermal analysis must be embedded within IC synthesis. This paper presents thermal analysis of the FCBGA chip with a 4mm×4mm×0.3mm silicon die. The silicon die dissipates heat flux of ...
U. Shukla, and D. Gupta
 Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Uttar Pradesh, India
One of the major challenges faced by the semiconductor industry is that electronic circuits produce a lot of heat energy during their operation. And with the current scenario where the gates are packed so much close together, then the problem of heat generation has become extremely significant. So we are working towards the efficient heat management and dissipation solution for the heat generated ...
K. K. Sriperumbudur, P. J. Koester, M. Stubbe, C. Tautorat, J. Held, W. Baumann, and J. Gimsa
 University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
 Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany
In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the transmembrane potential. To address this problem, we have developed new biosensor-chips with micro-structured needle electrodes (MNEs). MNE-penetration of single cells growing on the MNE-tips leads to a situation comparable to the whole-cell mode in classical Patch Clamp. MNE-penetration ...
A. Jeremic, T. Farncombe, S. Liu, and Y. Abdul-Rehman
Department of Electrical and Computer Engineering, McMaster University, Hamilton, Ontario, Canada
Department of Radiology, McMaster University, Hamilton, Ontario, Canada
Single photon emission computed tomography (SPECT) is a nuclear medicine imaging technique that uses gamma rays. It has been especially useful for bone scans, cardiac perfusion imaging, tumor scans and brain imaging. The main advantage of SPECT imaging is that it can target particular tissue receptors allowing one to focus on the imaging of the diseased tissue. In most cases Monte Carlo ...
E. R. Blatchley, and B.Z. Sun
Department of Civil Engineering, Purdue University, West Lafayette, IN, USA
Mineral precipitation on to the quartz surface of the lamp jackets in UV disinfection process (fouling) has been recognized as a major problem for UV radiation delivery during disinfection operation. Fouling behavior was observed to be induced thermally and influenced by hydraulic character of the UV disinfection configuration. Fouling process involves momentum, heat, and mass transport within ...
COMSOL Multiphysics® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology
F. Rossi and R. Pini
Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy
In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation mode and diffusion approximation were used to design a theoretical model of blue LED light interaction with an ...
Dependence of Potential and Ion Distribution on Electrokinetic Radius in Infinite and Finite-length Nano-channels
J. Schiffbauer, J. Fernandez, W. Booth, K. Kelly, A. Timperman, and B. Edwards
Physics Dept. West Virginia University, Morgantown, WV, USA
Chemical Engineering Dept,West Virginia University, Morgantown, WV, USA
Dept. of Chemistry, West Virginia University, Morgantown, WV, USA
A site-binding/dissociation model is used to determine surface charge in numerical studies of the equilibrium potential and ion distributions inside infinite and finite-length nano-channels. This COMSOL model allows us to investigate the response of surface (zeta) potential to environmental parameters such as reservoir salt concentration, solution pH and wall separation. The resulting ion and ...
M. Blaziková, J. Malínský, D. Stanek, and P. Herman
Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
Institute of Experimental Medicine, Prague, Czech Republic
Institute of Molecular Genetics, Prague, Czech Republic
Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the Cajal body. We have previously shown that the free diffusion model does not fully describe the snRNP motion ...
R. Umhack, M. Rainer, M. Tamerle, and G. Hillmer
Process-, Environmental- and Bio- technology, MCI - University of Applied Sciences, Innsbruck, Austria
A new type of radiator with a package of combs, to gain a larger area for heat exchange, instead of trapezoidal convector plates, is investigated. The main aim is to find the optimal comb diameter. To solve this problem, CFD (computational fluid dynamics) with COMSOL Multiphysics is used. A chart showing radiator power was produced, which includes radiator power for different temperatures and ...
S. Bellur, B. Agasanpura, and C. Coronella
Chemical and Metallurgical Engineering Department, University of Nevada, Reno, Nevada, USA
The aim of the present work is the formulation of a computational model describing transport phenomena in transient biosolids drying. COMSOL Multiphysics was used to perform the simulations, with two spatial dimensions. After a time step of 0.1 s, we found that the solid reached thermal equilibrium with the surrounding gas, which is consistent with empirical correlations.